| Midwestern State Mustangs Football vs. Missouri Southern State Lions | 8-29-2026
Saturday
5:00 PM | Memorial Stadium - Wichita in Wichita Falls, TX | View Tickets |
| Missouri Southern State Lions Football vs. Upper Iowa Peacocks | 9-5-2026
Saturday
TBD | Fred G. Hughes Stadium in Joplin, MO | View Tickets |
| Northwest Missouri State Bearcats Football vs. Missouri Southern State Lions | 9-19-2026
Saturday
1:30 PM | Bearcat Stadium in Maryville, MO | View Tickets |
| Missouri Southern State Lions Football vs. Central Missouri Mules | 9-26-2026
Saturday
TBD | Fred G. Hughes Stadium in Joplin, MO | View Tickets |
| Fort Hays State Tigers Football vs. Missouri Southern State Lions | 10-3-2026
Saturday
7:00 PM | Lewis Field Stadium in Hays, KS | View Tickets |
| Missouri Southern State Lions Football vs. Emporia State Hornets | 10-10-2026
Saturday
TBD | Fred G. Hughes Stadium in Joplin, MO | View Tickets |
| Nebraska-Kearney Lopers Football vs. Missouri Southern State Lions | 10-17-2026
Saturday
3:00 PM | Ron & Carol Cope Stadium in Kearney, NE | View Tickets |
| Missouri Western Griffons Football vs. Missouri Southern State Lions | 10-24-2026
Saturday
2:00 PM | Craig Field at Spratt Memorial Stadium in Saint Joseph, MO | View Tickets |
| Missouri Southern State Lions Football vs. Pittsburg State Gorillas | 10-31-2026
Saturday
TBD | Fred G. Hughes Stadium in Joplin, MO | View Tickets |
| Missouri Southern State Lions Football vs. Central Oklahoma Bronchos | 11-7-2026
Saturday
TBD | Fred G. Hughes Stadium in Joplin, MO | View Tickets |
| Washburn Ichabods Football vs. Missouri Southern State Lions | 11-14-2026
Saturday
TBD | Yager Stadium - KS in Topeka, KS | View Tickets |
